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The town of Seffner is located in the region Florida of United States.

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Seffner is a census-designated place (CDP) in Hillsborough County, Florida, United States. The population was 7,579 at the 2010 census, although its ZIP codes (33584 & 33583), whose boundaries extend beyond the ones given by the census and which include the places of Mango and a portion of Thonotosassa, have a population of around 35,000.

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