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The town of Irvine is located in the region Kentucky of United States.

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Irvine (local /ərvən/ and /ərvaɪn/) is a 4th-class city in Estill County, Kentucky, in the United States. It is the seat of its county. Its population was 2,715 at the time of the year 2010 U.S. census. It is located on the Kentucky River at the junction of Kentucky Route 52 and Kentucky Route 89.

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