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The town of Pascagoula is located in the region Mississippi of United States.

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Pascagoula is a city in Jackson County, Mississippi. It is the principal city of the Pascagoula, Mississippi Metropolitan Statistical Area, as a part of the Gulfport–Biloxi–Pascagoula, Mississippi Combined Statistical Area. The population was 26,200 at the 2000 census. It is the county seat of Jackson County.

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