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The town of Darlington is located in the region South Carolina of United States.

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Darlington is a small city in and the county seat of Darlington County, in the northeastern part of the U.S. state of South Carolina. It is a center for tobacco farming. The population was 6,289 at the 2010 census (12,066 total pop. of Darlington Urban Cluster in 2000) and is part of the Florence Metropolitan Statistical Area.

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